For those thinking about overall creativity, choosing a topic, and science in general, here are a few good reads.
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The importance of stupidity in scientific research by Martin Shwartz.
I really like this piece  which, despite the title, isn't really about stupidity, but about admitting that we don't know the answers to many interesting questions, and that this is what research is all about.

An advisor and his recently graduated student sit down together and think about Some tips for how to do science.  By Arjun Raj and Ed Ballister. 

 Innovation and creativity in zoology, George Bartholomew's 1982 essay.

Uri Alon writes up some advice on How to choose a good Scientific Question.